What does Brexit mean for the 2016 election?

So Britain (well, really, England and Wales), voted to leave the European Union Thursday. As the English would put it, this decision has created a small spot of bother in global financial markets and political capitals. Off the top of my head, the knock-on effects will include:
  1. A downward revision of British and global economic growth;
  2. Scotland holding a second referendum on independence;
  3. Other E.U. countries holding referendums on exiting the E.U. as well;
  4. The U.S. trade deficit worsening as the dollar’s strength increases even further;
  5. A lot of commentators freaking out even more about the possibility of a President Trump.